Reasons for the hybrid system not starting vary depending on the situation.
Check the following and perform the appropriate procedure:
The hybrid system will not start even though the correct starting procedure is being followed.
One of the following may be the cause of the problem:
Refuel the vehicle.
The interior lights and headlights are dim, or the horn does not sound or sounds at a low volume.
One of the following may be the cause of the problem:
The interior lights and headlights do not turn on, or the horn does not sound.
One of the following may be the cause of the problem:
Contact your Lexus dealer if the problem cannot be repaired, or if repair procedures are unknown.
Emergency start function
When the hybrid system does not start, the following steps can be used as an interim measure to start the hybrid system if the power switch is functioning normally.
Do not use this starting procedure except in cases of emergency.
1. Turn the power switch to ON mode and check that the parking brake is set.
2. Shift the shift lever to P.
3. Turn the power switch to ACCESSORY mode.
4. Press and hold the power switch for about 15 seconds while depressing the brake pedal firmly.
Even if the hybrid system can be started using the above steps, the system may be malfunctioning. Have the vehicle inspected by your Lexus dealer.
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not operate properlyLexus RX (RX 350L, RX450h) 2016-2025 Repair Manual > Blind Spot Monitor System: Slave Module Horizontal Axis Misalignment (C1AC2)
   DESCRIPTION This DTC is stored when the angle of the blind spot monitor sensor RH deviates more than the allowable range from the horizontal axis.  HINT:  
If a drum tester such as a speedometer tester, brake/speedometer combination tester or chassis dynamometer is used with the blind spot monitor s ...
   
Lexus RX (RX 350L, RX450h) 2016-2025 Repair Manual > Navigation System: USB Device Malfunction (B1585)
   DESCRIPTION This DTC is stored when a malfunction occurs in a connected device.    DTC No.   Detection Item   DTC Detection Condition   Trouble Area     B1585   USB Device Malfunction   When any of the following conditions is met:   
A non mass-storage class or incompatible protocol USB device is co ...